COVID VACCINE.. Only side-effect noticed so far is ‘fatigue’ or tiredness in some volunteers


NEW DELHI: The only noticeable side-effect for the vaccinea being administered for Covid control to select number of volunteers was fatigue in some cases. The UK is the first nation to give formal nod for vaccine injections, and the treatment is generally certified to be safe.

Top pharmaceutical companies that tested their vaccines on volunteers said the only Grade 3 (severe cases)-solicited adverse event greater than or equal to 2 per cent in frequency after the first or second dose “was fatigue at 3.7 per cent following dose 2.”

Interviewed by CNN, paediactrics professor Paul Offit at the Children’s Hospital of Philadelphia noted that some side effects are normal for all vaccines. “That means your immune response is working for you. You should feel good about that,” he said.

Should people experience side-effects from the first dose, then there shouldn’t be any difficulty coming back for that second shot, knowing that you’re now in a much better position to fight off this awful virus,” he was quoted as saying.

The Pfizer/BioNTech vaccine has been granted emergency authorisation by British regulators, and the first doses are expected to be rolled out from early next week.


The Pfizer/BioNTech vaccine uses a new approach to making vaccines that uses messenger RNA, or mRNA. The mRNA is a single strand of the genetic code that cells can “read” and use to make a protein. The mRNA instructs cells in the body to make a particular piece of the virus’s spike protein. The immune system sees it, recognizes it as foreign, and is prepared to attack when actual infection occurs.


The UK government says studies are underway to determine whether the AstraZeneca and Pfizer/BioNTech vaccines can be given interchangeably across the two doses, since “both … are based on the spike protein of the virus,” but so far it’s unclear whether this is effective.

“There is no evidence as to the interchangeability of the different Covid-19 vaccines although studies are underway. Therefore, every effort should be made to determine which vaccine the individual received and to complete with the same vaccine,” the UK government says, though exceptions are permitted. –Agencies, IHN-NN


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